Optimizing similarity factor of in vitro drug release profile for development of early stage formulation of drug using linear regression model

Journal of Mathematics in Industry

Table 4 Comparison of two drug release profiles of Venlafaxine HCl MR Tablets

Sample Data (Venlafaxine HCl MR Tablets)
Time (Hrs)	%Drug Release (DR)		Time(Hrs)	Predicted % Drug Release
X	Y1	Y2	X	Y1	Y2
1	17	13	1	17	13
2	23	18	2	23	18
4	29	25	3	26	19
6	37	31	4	29	25
8	41	35	5	30	26
12	46	41	6	37	31
16	52	57	7	34	32
18	58	68	8	41	35
20	65	79	9	39	39
24	72	94	10	41	42
			11	43	45
			12	46	41
			14	50	55
			16	52	57
			18	58	68
			20	65	79
			24	72	94
f2	50.34		54.98